| Pitchers | Team | IP |
| Kodai Senga | NYM | 166.1 |
| Ryne Nelson | ARI | 144.0 |
| Tanner Bibee | CLE | 142.0 |
| J.P. France | HOU | 136.1 |
| Bryce Miller | SEA | 131.1 |
| Griffin Canning | LAA | 127.0 |
| Tylor Megill | NYM | 126.1 |
| Logan Allen | CLE | 125.1 |
| Colin Rea | MIL | 124.2 |
| Bobby Miller | LAD | 124.1 |
| Luke Weaver | CIN / SEA / NYY | 123.2 |
| Grayson Rodriguez | BAL | 122.0 |
| Jake Irvin | WSN | 121.0 |
| Brandon Williamson | CIN | 117.0 |
| Luis Medina | OAK | 109.2 |
| Andrew Abbott | CIN | 109.1 |
| Taj Bradley | TBR | 104.2 |
| Reese Olson | DET | 103.2 |
| Cole Ragans | KCR / TEX | 96.0 |
| Brandon Pfaadt | ARI | 96.0 |
| James Paxton | BOS | 96.0 |
| Xzavion Curry | CLE | 95.0 |
| Eury Pérez | MIA | 91.1 |
| Jhony Brito | NYY | 90.1 |
| Zack Littell | BOS / TBR | 90.0 |
| Jake Bird | COL | 89.1 |
| Ben Lively | CIN | 88.2 |
| Bryan Woo | SEA | 87.2 |
| Connor Seabold | COL | 87.1 |
| Peter Lambert | COL | 87.1 |
| Luis Ortiz | PIT | 86.2 |
| Tyler Holton | DET | 85.1 |
| Tristan Beck | SFG | 85.0 |
| Yonny Chirinos | TBR / ATL | 85.0 |
| Jesse Scholtens | CHW | 85.0 |
| Jaime Barria | LAA | 82.1 |
| Gavin Williams | CLE | 82.0 |
| Bailey Falter | PHI / PIT | 80.2 |
| Brandon Bielak | HOU | 80.0 |
| Michael Tonkin | ATL | 80.0 |
| Shintaro Fujinami | OAK / BAL | 79.0 |
| Ty Blach | COL | 78.0 |
| Kyle Muller | OAK | 77.0 |
| Ian Gibaut | CIN | 75.2 |
| Justin Lawrence | CHC | 75.0 |
| Alec Mills | KCR | 74.1 |
| Yennier Cano | BAL | 72.2 |
| Julian Merryweather | CHC | 72.0 |
| Julio Teheran | MIL | 71.2 |
| Matthew Boyd | DET | 71.0 |
| Bryan Hoeing | MIA | 70.2 |
| Scott McGough | ARI | 70.1 |
| Carlos Hernandez | KCR | 70.0 |
| Justin Topa | SEA | 69.0 |
| Kevin Kelly | TBR | 67.0 |
| Gregory Santos | CHW | 66.1 |
| Fernando Cruz | CIN | 66.0 |
| Jose Cuas | KCR / CHC | 65.1 |
| Mike Baumann | BAL | 64.2 |
| Alex Faedo | DET | 64.2 |
| Hogan Harris | OAK | 63.0 |
| Pierce Johnson | COL / ATL | 62.2 |
| Elvis Peguero | MIL | 61.1 |
| Ryan Walker | SFG | 61.1 |
| Andre Jackson | PIT / LAD | 61.1 |
| Lucas Sims | CIN | 61.0 |
| Drew VerHagen | STL | 61.0 |
| James Kaprielian | OAK | 61.0 |
| Emmet Sheehan | LAD | 60.1 |
| Kirby Yates | ATL | 60.1 |
| Erasmo Ramirez | TBR / WSN | 60.1 |
| Jose Cisnero | DET | 59.1 |
| Albert Abreu | NYY | 59.0 |
| Taylor Clarke | KCR | 59.0 |
| Collin McHugh | ATL | 58.2 |
| Dauri Moreta | PIT | 58.0 |
| Ian Hamilton | NYY | 58.0 |
| Ryan Weathers | SDP / MIA | 57.2 |
| Andrew Nardi | MIA | 57.1 |
| Cody Bradford | TEX | 56.0 |
| Mason Englert | DET | 56.0 |
| Derek Law | CIN | 55.0 |
| Lucas Erceg | OAK | 55.0 |
| Adrian Martinez | OAK | 55.0 |
| Gabe Speier | SEA | 54.2 |
| Dominic Leone | NYM / LAA / SEA | 54.0 |
| Jacob Webb | LAA / BAL | 53.2 |
| Alex Young | CIN | 53.2 |
| Jared Shuster | ATL | 52.2 |
| Jeff Hoffman | PHI | 52.1 |
| Brent Honeywell Jr. | SDP / CHS | 52.1 |
| Josh Sborz | TEX | 52.1 |
| George Soriano | MIA | 52.0 |
| Ronel Blanco | HOU | 52.0 |
| Josh Fleming | TBR | 51.2 |
| Danny Coulombe | BAL | 51.1 |
| Tom Cosgrove | SDP | 51.1 |
| Brennan Bernardino | BOS | 50.2 |
| Keynan Middleton | CHS / NYY | 50.2 |
| Jose Hernandez* | PIT | 50.2 |
| Osvaldo Bido | PIT | 50.2 |
| Pedro Avila | SDP | 50.1 |
| Quinn Priester | PIT | 50.0 |
| Andres Machado | WSN | 50.0 |
| Daniel Bard | COL | 49.1 |
| Aaron Loup | LAA | 48.2 |
| Andrew Vasquez | PHI / DET | 48.1 |
| Scott Alexander | SFG | 48.1 |
| Yency Almonte | LAD | 48.0 |
| Tayler Saucedo | SEA | 47.2 |
| Chris Murphy | BOS | 47.2 |
| Trevor May | OAK | 46.2 |
| Sam Long | OAK | 45.0 |
| Chasen Shreve | DET / CIN | 44.2 |
| Jose Urena | CHW / COL | 44.2 |
| Jose Ruiz | ARI / CHS | 44.1 |
| Tim Hill | SDP | 44.1 |
| Ryan Feltner | COL | 43.1 |
| Dylan Covey | PHI / LAD | 43.0 |
| Angel Zerpa | KCR | 42.2 |
| Chris Devenski | LAA / TBR | 42.1 |
| Keaton Winn | SFG | 42.1 |
| Jalen Beeks | TBR | 42.1 |
| Jovani Moran | MIN | 42.1 |
| Shelby Miller | LAD | 42.0 |
| José Butto | NYM | 42.0 |
| José Soriano | LAA | 42.0 |
| Hunter Gaddis | CLE | 42.0 |
| Matt Waldron | SDP | 41.1 |
| Drey Jameson | ARI | 40.2 |
| Nick Ramirez | NYY | 40.2 |
| Tommy Kahnle | NYY | 40.2 |
| Brendan White | DET | 40.2 |
| Ryan Borucki | PIT | 40.1 |
| Michael Rucker | CHC | 40.1 |
| Yunior Marte | PHI | 39.1 |
| Cory Abbott | WSN | 39.1 |
| Joe Mantiply | ARI | 39.0 |
| Matt Koch | COL | 38.2 |
| Chad Kuhl | WSN | 38.1 |
| Yohan Ramirez | PIT / CHS | 38.1 |
| Randy Vásquez | NYY | 37.2 |
| Jeff Brigham | NYM | 37.2 |
| Jimmy Lambert | CHW | 37.2 |
| Dallas Keuchel | MIN | 37.2 |
| John King | TEX / STL | 37.1 |
| Peter Strzelecki | MIL / ARI | 37.0 |
| JoJo Romero | STL | 36.2 |
| Bowden Francis | TOR | 36.1 |
| Carmen Mlodzinski | PIT | 36.0 |
| Austin Cox | KCR | 35.2 |
| Grant Anderson | TEX | 35.2 |
| Grant Hartwig | NYM | 35.2 |
| Nick Anderson | ATL | 35.1 |
| Thaddeus Ward | WSN | 35.1 |
| Karl Kauffmann | COL | 35.0 |
| Mauricio Llovera | BOS / SFG | 35.0 |
| Jordan Wicks | CHC | 34.2 |
| Kyle Harrison | SFG | 34.2 |
| Austin Voth | BAL | 34.2 |
| Josh Winder | MIN | 34.2 |
| Peyton Battenfield | CLE | 34.2 |
| Dylan Dodd | ATL | 34.1 |
| Nick Lodolo | CIN | 34.1 |
| Jose Ferrer | WSN | 34.0 |
| Victor Gonzalez | LAD | 33.2 |
| Drew Rom | STL | 33.2 |
| Gavin Hollowell | COL | 33.2 |
| Jose Suarez | LAA | 33.2 |
| Mason Miller | OAK | 33.1 |
| Luke Jackson | SFG | 33.1 |
| Kenny Rosenberg | LAA | 33.0 |
| Cooper Criswell | TBR | 33.0 |
| Jimmy Cordero | NYY | 32.2 |
| Joe La Sorsa | TBR / WAS | 32.2 |
| Allan Winans | ATL | 32.1 |
| Robert Garcia | WSN / MIA | 32.0 |
| Daniel Duarte | CIN | 31.2 |
| Gavin Stone | LAD | 31.0 |
| Luis Frías | ARI | 31.0 |
| Abner Uribe | MIL | 30.2 |
| Caleb Thielbar | MIN | 30.2 |
| Richard Bleier | BOS | 30.2 |
| Noah Davis | COL | 30.0 |
| Jay Jackson | TOR | 29.2 |
| Angel Perdomo | PIT | 29.0 |
| Sean Hjelle | SFG | 29.0 |
| Connor Brogdon | PHI | 29.0 |
| Nick Wittgren | KCR | 29.0 |
| Isaiah Campbell | SEA | 28.2 |
| Thomas Hatch | TOR / PIT | 28.2 |
| Daniel Palencia | CHC | 28.1 |
| Justin Bruihl | LAD / COL | 28.0 |
| Jackson Kowar | KCR | 28.0 |
| Brock Stewart | MIN | 27.2 |
| Andrew Suárez | STL | 27.2 |
| Dinelson Lamet | COL / BOS | 27.2 |
| Tim Herrin | CLE | 27.2 |
| Casey Lawrence | STL | 27.1 |
| Slade Cecconi | ARI | 27.0 |
| Ray Kerr | SDP | 27.0 |
| Zach Neal | OAK | 27.0 |
| Joe Jacques | BOS | 26.2 |
| Mike Mayers | KCR | 26.1 |
| Luis Cessa | CIN | 26.0 |
| Calvin Faucher | TBR | 25.2 |
| Stephen Nogosek | NYM | 25.2 |
| Brent Headrick | MIN | 25.2 |
| AJ Smith-Shawver | ATL | 25.1 |
| Andrew Bellatti | PHI | 24.2 |
| Duane Underwood Jr. | PIT | 24.1 |
| Yerry De Los Santos | PIT | 24.1 |
| Amir Garrett | KCR | 24.1 |
| Amos Willingham | WSN | 24.1 |
| Jordan Balazovic | MIN | 24.1 |
| Kevin Herget | CIN | 24.1 |
| Matt Carasiti | COL | 24.1 |
| Colin Selby | PIT | 24.0 |
| Bryce Jarvis | ARI | 23.2 |
| Keegan Akin | BAL | 23.2 |
| Tommy Doyle | COL | 23.2 |
| Tommy Hunter | NYM | 23.2 |
| Richard Lovelady | OAK | 23.1 |
| James McArthur | KCR | 23.1 |
| Brandon Walter | BOS | 23.0 |
| Kaleb Ort | BOS | 23.0 |
| Devin Smeltzer | MIA | 22.1 |
| Nick Robertson | BOS / LAD | 22.1 |
| Luis Patino | TBR / CHS | 21.2 |
| Cole Sands | MIN | 21.2 |
| Matt Barnes | MIA | 21.1 |
| Cody Bolton | PIT | 21.1 |
| Zach Plesac | CLE | 21.1 |
| Connor Phillips | CIN | 20.2 |
| Drew Carlton | SDP | 20.2 |
| Rob Zastryzny | PIT | 20.2 |
| Adam Cimber | TOR | 20.2 |
| Darius Vines | ATL | 20.1 |
| Collin Snider | KCR | 20.1 |
| Gus Varland | MIL / LAD | 20.1 |
| Max Castillo | KCR | 20.1 |
| Sawyer Gipson-Long | DET | 20.0 |
| Sammy Peralta | CHW | 20.0 |
| Greg Weissert | NYY | 20.0 |
| Jackson Rutledge | WSN | 20.0 |
| Josh Staumont | KCR | 20.0 |
| Lane Ramsey | CHW | 20.0 |
| Anthony Bass | TOR | 20.0 |
| Adam Oller | OAK | 19.2 |
| Denyi Reyes | NYM | 19.2 |
| Reed Garrett | BAL / NYM | 19.2 |
| John Curtiss | NYM | 19.2 |
| Hitters | Team | AB |
| Ezequiel Tovar | COL | 581 |
| Anthony Volpe | NYY | 541 |
| Masataka Yoshida | BOS | 537 |
| James Outman | LAD | 483 |
| Maikel Garcia | KCR | 464 |
| Esteury Ruiz | OAK | 449 |
| Will Brennan | CLE | 432 |
| Jordan Walker | STL | 420 |
| Ryan Noda | OAK | 406 |
| Brice Turang | MIL | 404 |
| Brenton Doyle | COL | 399 |
| Elly De La Cruz | CIN | 388 |
| Francisco Alvarez | NYM | 382 |
| Jace Peterson | OAK / ARI | 374 |
| Connor Wong | BOS | 371 |
| Joey Wiemer | MIL | 367 |
| Matt McLain | CIN | 365 |
| Andy Ibanez | DET | 356 |
| Yainer Diaz | HOU | 355 |
| Brett Baty | NYM | 353 |
| Mike Moustakas | COL / LAA | 352 |
| Ryan O'Hearn | BAL | 346 |
| Edouard Julien | MIN | 338 |
| Mike Tauchman | CHC | 337 |
| Ji Hwan Bae | PIT | 334 |
| Patrick Bailey | SFG | 326 |
| Alec Burleson | STL | 315 |
| Gabriel Arias | CLE | 315 |
| Mickey Moniak | LAA | 311 |
| Blake Sabol | SFG | 310 |
| Yuli Gurriel | MIA | 299 |
| Corey Julks | HOU | 298 |
| Zach Neto | LAA | 289 |
| Eduardo Escobar | NYM / LAA | 288 |
| Will Benson | CIN | 287 |
| Brandon Crawford | SFG | 283 |
| Andruw Monasterio | MIL | 282 |
| Jordan Diaz | OAK | 272 |
| Zack Gelof | OAK | 270 |
| Miguel Vargas | LAD | 256 |
| Casey Schmitt | SFG | 253 |
| Josh Palacios | PIT | 247 |
| Travis Jankowski | TEX | 247 |
| Oscar Colás | CHW | 245 |
| Jake Bauers | NYY | 242 |
| Jacob Stallings | MIA | 241 |
| Trey Mancini | CHC | 235 |
| José Caballero | SEA | 231 |
| Luis Matos | SFG | 228 |
| Henry Davis | PIT | 225 |
| Kolten Wong | SEA / LAD | 224 |
| Christian Encarnacion-Strand | CIN | 222 |
| Zack Short | DET | 221 |
| Mark Vientos | NYM | 218 |
| Royce Lewis | MIN | 217 |
| Freddy Fermin | KCR | 217 |
| Jordan Westburg | BAL | 208 |
| Tucupita Marcano | PIT | 202 |
| Liover Peguero | PIT | 198 |
| Bo Naylor | CLE | 198 |
| Kevin Pillar | ATL | 197 |
| Sal Frelick | MIL | 191 |
| Matt Carpenter | SDP | 188 |
| Endy Rodríguez | PIT | 186 |
| Logan O'Hoppe | LAA | 182 |
| Jared Triolo | PIT | 181 |
| Austin Barnes | LAD | 178 |
| Seby Zavala | CHW / ARI | 175 |
| Oswald Peraza | NYY | 173 |
| Dominic Canzone | ARI / SEA | 173 |
| Carlos Pérez | OAK | 168 |
| Pablo Reyes | BOS | 167 |
| Lenyn Sosa | CHW | 164 |
| Luis Campusano | SDP | 163 |
| DJ Stewart | NYM | 160 |
| Jake Alu | WSN | 159 |
| Chad Wallach | LAA | 157 |
| Trayce Thompson | LAD / CHW | 153 |
| Francisco Mejia | TBR | 150 |
| Johan Rojas | PHI | 149 |
| Raimel Tapia | BOS / MIL / TBR | 148 |
| Zach Remillard | CHW | 147 |
| Tom Murphy | SEA | 145 |
| Corey Dickerson | WSN | 144 |
| Luis Urias | MIL / BOS | 144 |
| Blake Perkins | MIL | 143 |
| Nelson Cruz | SDP | 143 |
| Cam Gallagher | CLE | 143 |
| Michael Toglia | COL | 141 |
| Enmanuel Valdez | BOS | 139 |
| Kody Clemens | PHI | 139 |
| Rougned Odor | SDP | 138 |
| Jonathan Schoop | DET | 136 |
| Kevin Smith | OAK | 135 |
| Willie Calhoun | NYY | 134 |
| Miles Mastrobuoni | CHC | 133 |
| Jose Barrero | CIN | 133 |
| Miguel Amaya | CHC | 131 |
| Austin Wynns | SFG / LAD / COL | 130 |
| Austin Nola | SDP | 130 |
| Billy McKinney | NYY | 128 |
| Wil Myers | CIN | 127 |
| Tyler Soderstrom | OAK | 125 |
| Parker Meadows | DET | 125 |
| David Villar | SFG | 124 |
| Dairon Blanco | KCR | 124 |
| Mike Zunino | CLE | 124 |
| Lawrence Butler | OAK | 123 |
| Masyn Winn | STL | 122 |
| Matthew Batten | SDP | 120 |
| Brett Wisely | SFG | 120 |
| Davis Schneider | TOR | 116 |
| Nick Gonzales | PIT | 115 |
| Noelvi Marte | CIN | 114 |
| Garrett Stubbs | PHI | 113 |
| Nolan Schanuel | LAA | 109 |
| Alfonso Rivas | SDP / PIT | 109 |
| Avisail Garcia | MIA | 108 |
| Jacob Young | WSN | 107 |
| Jackie Bradley Jr. | KCR | 105 |
| Jesus Aguilar | OAK | 104 |
| Ji-Man Choi | PIT / SDP | 104 |
| Rene Pinto | TBR | 103 |
| Ronny Mauricio | NYM | 101 |
| Alika Williams | PIT | 101 |
| David Fry | CLE | 101 |
| Tyler Nevin | DET | 95 |
| Eric Hosmer | CHC | 94 |
| Everson Pereira | NYY | 93 |
| Dominic Fletcher | ARI | 93 |
| Richie Palacios | STL | 93 |
| Romy Gonzalez | CHW | 93 |
| Jose Azocar | SDP | 91 |
| Jon Singleton | MIL / HOU | 91 |
| Nick Gordon | MIN | 91 |
| Jonathan Davis | MIA | 90 |
| Matt Mervis | CHC | 90 |
| David Fletcher | LAA | 89 |
| Cade Marlowe | SEA | 88 |
| Jonah Bride | OAK | 88 |
| Osleivis Basabe | TBR | 87 |
| Jonathan Aranda | TBR | 87 |
| Luken Baker | STL | 86 |
| David Hensley | HOU | 84 |
| Miguel Andujar | PIT | 84 |
| Curtis Mead | TBR | 83 |
| Ceddanne Rafaela | BOS | 83 |
| Brayan Rocchio | CLE | 81 |
| Brett Sullivan | SDP | 81 |
| Andrew Velazquez | LAA | 81 |
| Curt Casali | CIN | 80 |
| Xavier Edwards | MIA | 79 |
| Brandon Dixon | SDP | 79 |
| Jordan Luplow | TOR / MIN | 77 |
| Wilyer Abreu | BOS | 76 |
| Taylor Motter | STL | 76 |
| Jake Marisnick | CHW / DET / LAD | 76 |
| Henry Ramos | CIN | 74 |
| Yonathan Daza | COL | 74 |
| Connor Capel | OAK | 73 |
| Mike Brosseau | MIL | 73 |
| Michael Busch | LAD | 72 |
| Nick Martini | CIN | 72 |
| Hunter Goodman | COL | 70 |
| Austin Wells | NYY | 70 |
| Franchy Cordero | NYY | 69 |
| Luke Voit | MIL | 68 |
| Ben Rortvedt | NYY | 68 |
| Dane Myers | MIA | 67 |
| Clint Frazier | CHW | 66 |
| Garrett Mitchell | MIL | 65 |
| Danny Mendick | NYM | 65 |
| Korey Lee | CHW | 65 |
| Brett Phillips | LAA | 63 |
| Evan Carter | TEX | 62 |
| Nick Loftin | KCR | 62 |
| Michael Stefanic | LAA | 62 |
| Jason Vosler | CIN | 62 |
| Mark Mathias | PIT / SFG | 62 |
| Colton Cowser | BAL | 61 |
| Estevan Florial | NYY | 61 |
| Matt Beaty | SFG / KCR | 61 |
| Samad Taylor | KCR | 60 |
| Jonathan Araúz | NYM | 59 |
| Franmil Reyes | KCR | 59 |
| Brad Miller | TEX | 56 |
| Heliot Ramos | SFG | 56 |
| Tim Locastro | NYM | 56 |
| Wade Meckler | SFG | 56 |
| Tomas Nido | NYM | 56 |
| Darick Hall | PHI | 54 |
| Bubba Thompson | TEX | 53 |
| Trey Cabbage | LAA | 53 |
| Nate Eaton | KCR | 53 |
| José Fermín | STL | 51 |
| Tyler Wade | OAK | 51 |
| Ernie Clement | TOR | 50 |